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Effects include reduced inflammatory markers in synovial fluid, preserved cartilage thickness on imaging, improved joint function scoring

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10.4093/dmj.2019.0185 66 GreenH.TsitsiP.MarkakiI.AarslandD.SvenningssonP

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doi: 10.1158/1055-9965.EPI-08-1094 18 McLaughlinSAStaleyACViciniFThiruchelvamPHutchisonNAMendezJet al

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The clinical evidence, while not entirely conclusive, suggests a cautious approach to semaglutide use, especially in patients with a history of yeast infections or other risk factors

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Safety and considerations There is not enough high-quality, modern human safety data to make broad safety claims about DSIP, and that uncertainty is itself part of the clinical picture

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